Anti-Aging Breakthroughs and Lifestyle Interventions to Slow Aging Now

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• Future of Anti-Aging Research
• Longevity Medicine in Clinical Practice
• Lifestyle Interventions for Rejuvenation
• Early Awareness of Aging Changes
• Never Too Late For Change
• Full Transcript

Future of Anti-Aging Research

Dr. Andrea Maier, MD, outlines the exciting trajectory of anti-aging research. She hopes the field will move beyond discussion to widespread clinical application. Dr. Andrea Maier, MD, notes that numerous clinical trials for anti-aging compounds are currently underway. This includes research into well-known candidates like metformin and rapamycin. The immense attention on longevity science is accelerating the development of effective interventions.

Longevity Medicine in Clinical Practice

Dr. Andrea Maier, MD, is a physician in internal medicine. She positions longevity medicine as a vital component of this specialty. Her aim is to integrate evidence-based longevity practices into general clinical care within three to five years. A key pillar is the ability to accurately detect biological age using valid markers. Dr. Maier and a growing community of specialists are working to make these advancements standardized and affordable for entire populations, not just the wealthy.

Lifestyle Interventions for Rejuvenation

Dr. Andrea Maier, MD, emphasizes a potent, non-pharmaceutical action available today: lifestyle intervention. She states that increasing physical activity and reducing sedentary behavior can directly rejuvenate cells in the body. These interventions are proven to lower biological age at all stages of life. During his conversation with Dr. Maier, Dr. Anton Titov, MD, explores these actionable strategies. This highlights that powerful tools to slow aging are already within reach.

Early Awareness of Aging Changes

A critical piece of wisdom from Dr. Andrea Maier, MD, is that aging starts very early. Functional decline is measurable long before major changes become apparent in middle age. She advises individuals to be aware of these changes at a young age. Proactive measures taken early can have a significant impact on long-term healthspan. This early awareness is a foundational principle for successful longevity medicine.

Never Too Late For Change

Dr. Andrea Maier, MD, offers an profoundly optimistic message: it is never too late to make positive changes. She references studies conducted on nonagenarians and centenarians that show the body's remarkable adaptability. Interventions like strength training and resistance exercise can improve cardiovascular fitness and overall shape even at very advanced ages. Dr. Maier concludes her discussion with Dr. Anton Titov, MD, by reinforcing that great outcomes are possible at any age by starting the right interventions.

Full Transcript

Dr. Anton Titov, MD: Professor Maier, what is the future in anti-aging research? Will we continue talking about metformin and rapamycin, caloric restrictions ten years from now? What is on the horizon? Where do you think the breakthroughs are likely to come from?

Dr. Andrea Maier, MD: Hopefully, we will not talk about it, but we will do it. So that is my aim as a physician. I am a physician in internal medicine; longevity medicine is part of internal medicine. It's part of general practitioners that they apply it, hopefully in the next coming three to five years.

That should be feasible in clinical practice because we can already detect the biological age. We are very good now at the point that we say, okay, these are valid markers. Diagnosing is one thing. But there are many clinical trials of anti-aging compounds ongoing, and there's so much attention to the longevity field that we can also intervene.

That's very important. You shouldn't forget that we already have a very potent action. It's not a drug, but it's lifestyle interventions, which we do not do well yet. But we know that, for example, increasing physical activity in certain individuals and reducing sedentary behavior is already rejuvenating cells in the body. It already works.

And we know that we can lower the biological age at all stages of life. So hopefully, I will do my best, together with my other colleagues, internal medicine specialists or neurologists, psychiatrists. There's a huge community that is now shaping longevity medicine.

We are bringing it into clinical practice in a very standardized way, being evidence-based. It's affordable. Hopefully, it's affordable for not only the rich people but for the entire population and society, because that's what we need.

Dr. Anton Titov, MD: Is there anything else in your interests, experience, and wisdom that you could share with our viewers?

Dr. Andrea Maier, MD: Absolutely. I would just highlight that aging starts very early. We know that the functional decline is already measurable at the age of your own life and health; please do not wait until you're 40 or 50 when you see that there are major changes in the body. So be aware of changes already at a quite early age.

The second thing I would like to highlight is that it's never too late to make changes to your life. For example, changing lifestyle—we do lots of studies and did lots of studies in the past, including in nonagenarians or centenarians, where we have very old individuals. They said, okay, let me get into a better shape.

I can tell you, for example, about strength training, resistance exercise training, cardiovascular fitness. It helps the body even at higher ages; it is adaptable. You will have great outcomes if you do the right thing. We see aging as a continuum within a life circle, but it's never too late to make changes and start.

This is an optimistic note that should be followed by people irrespective of their age.

Dr. Anton Titov, MD: Thank you very much, Professor Maier. Thank you very much for this most useful conversation. It's been very helpful and informative, and we hope to come back to you in the future for more news on longevity research. Thank you so much!

Dr. Andrea Maier, MD: Thank you for having me.